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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MKNK2
All Species:
26.36
Human Site:
S452
Identified Species:
52.73
UniProt:
Q9HBH9
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HBH9
NP_060042.2
465
51875
S452
A
Q
R
R
Q
R
A
S
L
S
S
A
P
V
V
Chimpanzee
Pan troglodytes
XP_512248
805
84821
S779
A
Q
R
R
Q
R
A
S
L
S
S
A
P
V
V
Rhesus Macaque
Macaca mulatta
XP_001117579
489
54064
S476
A
Q
R
R
Q
R
A
S
L
S
S
A
P
V
V
Dog
Lupus familis
XP_855041
1044
109683
S1031
A
Q
R
R
Q
R
A
S
L
S
A
A
P
V
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDB0
459
51614
S446
A
Q
R
R
Q
R
A
S
L
S
A
T
P
V
V
Rat
Rattus norvegicus
Q5U2N4
459
51555
S446
A
Q
R
R
Q
R
A
S
L
S
A
T
P
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235171
508
56331
H493
A
K
R
R
A
M
T
H
A
T
K
N
S
D
F
Frog
Xenopus laevis
Q6P431
467
52653
S450
A
K
R
R
Q
Q
G
S
K
G
G
I
S
P
P
Zebra Danio
Brachydanio rerio
NP_997888
472
52923
S446
A
H
R
R
K
T
A
S
S
Q
H
R
G
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_731624
1090
123424
Q1073
L
Q
R
R
L
R
Q
Q
Q
R
A
N
D
L
S
Honey Bee
Apis mellifera
XP_395927
516
58135
R498
M
Q
R
R
L
K
A
R
S
D
L
L
E
R
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_779905
511
56921
H499
A
K
R
R
A
A
M
H
S
Q
G
R
D
Q
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.8
92.4
34.6
N.A.
92.6
92.6
N.A.
N.A.
60.8
76.8
73.3
N.A.
24
49.8
N.A.
48.7
Protein Similarity:
100
48.5
93.4
36.8
N.A.
95.2
95.2
N.A.
N.A.
73
87.7
84.5
N.A.
31
66.6
N.A.
64.5
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
20
33.3
40
N.A.
26.6
26.6
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
33.3
46.6
46.6
N.A.
40
33.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
84
0
0
0
17
9
67
0
9
0
34
34
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
0
0
0
0
0
0
0
9
0
0
17
9
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
0
0
0
0
0
9
0
0
9
17
0
9
0
0
% G
% His:
0
9
0
0
0
0
0
17
0
0
9
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% I
% Lys:
0
25
0
0
9
9
0
0
9
0
9
0
0
0
0
% K
% Leu:
9
0
0
0
17
0
0
0
50
0
9
9
0
9
0
% L
% Met:
9
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
50
17
9
% P
% Gln:
0
67
0
0
59
9
9
9
9
17
0
0
0
9
9
% Q
% Arg:
0
0
100
100
0
59
0
9
0
9
0
17
0
9
0
% R
% Ser:
0
0
0
0
0
0
0
67
25
50
25
0
17
0
9
% S
% Thr:
0
0
0
0
0
9
9
0
0
9
0
17
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
59
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _